Izzie and George Leaving Grey's Anatomy

The actors of Grey's Anatomy find themselves in more trouble than their characters do in the show. Former Grey's star Isaiah Washington was fired after disrespecting fellow cast mates and current cast member Justin Chambers found himself checking into UCLA psych ward after reporting issues with sleep last year. James Pickens Jr. spoke out about his costars and claims that both Katherine Heigl and T.R. Knight are leaving Grey's Anatomy.

It has been obvious that Katherine Heigl has been unhappy with the writers at Grey's Anatomy because this past summer she proclaimed she did not want another Emmy. Heigl said, "I did not feel that I was given the material this season to warrant an Emmy nomination and in an effort to maintain the integrity of the academy organization. In addition, I did not want to potentially take away an opportunity from an actress who was given such materials."

The BFF's in real life work as a team on screen and off and it seems like this team is hitting the road. US Weekly asked James Pickens Jr. who plays Chief Webber if Heigl is planning on leaving Grey's. His response, "Yes, she is. Wherever Katherine goes, I wish her nothing but the best." At a recent NCAAP luncheon Pickens spoke out about T.R. Knight, ""He's going too." What will Grey's Anatomy be like without Dr. Stevens and Dr. O'Mallay?